Portfolio

Selected Publications

Our research team publishes findings in leading peer-reviewed journals, contributing to neurovascular research advancement.

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model
Doheim MF, Mohammaden MH, Abdelhamid H, et al.
Annals of Neurology. 2026;99:1198-1209
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Impact of an Artificial Intelligence-Driven Triage System on Workflow and Transfer Efficiency: 4,548 Admissions to Four Thrombectomy Hubs Receiving Transfers from Sixty Spokes
Doheim MF, Starr M, Bhatt NR, et al.
J Neurol Neurosurg Psychiatry. 2026
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Exploring Between-Study Heterogeneity in Extended-Window IV Thrombolysis for Acute Ischemic Stroke: A Meta-Analysis of 18 Randomized Controlled Trials
Doheim MF, Al-Qudah AM, Singh R, et al.
Neurology. 2026
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From Gums to Brain: Unveiling the Hidden Inflammatory Connection Between Periodontal and Cerebrovascular Diseases
Lima JC*, Doheim MF*, Nogueira CCS, Sen S, Nogueira RG.
Stroke. 2026 (*co-first authors)
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Feasibility of emergent single-step intracranial self-expanding stent deployment using over-the-wire coronary balloons...
Al-Bayati AR, Doheim MF, Mohammaden MH, et al.
J Neurointerv Surg. 2025
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Meta-Analysis of Randomized Controlled Trials on IV Thrombolysis in Patients With Minor Acute Ischemic Stroke
Doheim MF, Nguyen TN, Xiong Y, et al.
Neurology. 2025
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Adjunctive Thrombolytics After Successful Endovascular Reperfusion: A Systematic Review and Meta-Analysis
Doheim MF, Mohammaden MH, Jumah A, et al.
Annals of Neurology. 2025
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Association of anesthesia strategies with outcomes in endovascular treatment for distal and medium vessel occlusions
Doheim MF, Knapen RR, et al.
European Stroke Journal. 2025
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Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery
Doheim MF, Knapen RRMM, et al.
Stroke. 2025
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Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis
Nogueira RG, Jovin TG, Liu X, et al.
The Lancet. 2025
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Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review...
Jovin TG, Nogueira RG, Lansberg MG, et al.
Lancet. 2022
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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct
Nogueira RG, Jadhav AP, Haussen DC, et al.
N Engl J Med. 2018
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Distal Medium Vessel Occlusion Strokes: Understanding the Present and Paving the Way
Nogueira RG, Doheim MF, et al.
Journal of Stroke. 2024
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Trials

Enrolling

The DUSK Trial

Phase III randomized trial of thrombectomy versus standard medical therapy for distal medium vessel occlusion stroke. Active and enrolling: 584 patients, up to 50 sites. NCT05983757.

About DUSK

More trials in preparation

Our Clinical Trials Unit is preparing further multicenter trials, pending funding.

Clinical Trials Unit

Collaborations

Patient-level pooled analysis

VERITAS

The patient-level pooled analysis of the four vertebrobasilar thrombectomy trials: BEST, BASICS, ATTENTION and BAOCHE.

  • Nogueira RG, Jovin TG, Liu X, et al. Lancet 2025;405:61-69. Read
  • Related: our pooled analysis of thrombolysis before thrombectomy in basilar artery occlusion, Cardiovascular and Interventional Radiology 2025.

Statistical collaborations

With our Statistical and Data Science Core Lab: ATLAS ER, the RESILIENT trials and HEMERA-1.

About the core

Ongoing Projects

Active Development
NeuroSmart AI
Tech ID: 07112
AI-driven clinical decision support delivering personalized, real-time stroke care guidance using ML and real-world data.
Learn More →
In Development
Device Innovation for Neurovascular Diseases
Novel neurovascular device development improving treatment options for patients with complex cerebrovascular conditions.
Active Enrollment
DUSK Trial
NCT05983757
Combined Thrombectomy for Distal Medium Vessel Occlusion Stroke - Phase-3 multicenter study examining endovascular thrombectomy outcomes.
View Trial →