Cores

Our cores

Each core takes part of the journey from evidence to solution. Together they let one question become a trial, a model, a device or a company.

Clinical Trials Unit

Investigator-initiated multicenter trials, led end to end.

What we offer

  • Trial design and protocol development
  • FDA regulatory strategy, including IDE and IND submissions
  • Coordinating-center leadership and project management
  • Site activation, monitoring and safety oversight
  • Data management and randomization systems
  • Analysis, reporting and publication

Flagship

DUSK, a phase III trial of thrombectomy for distal medium vessel occlusion stroke (about DUSK). More trials are planned, pending funding.

Statistical and Data Science Core Lab

A service core for multicenter collaborations.

What we offer

  • Statistical analysis plans
  • Registries and data harmonization
  • Causal inference and treatment-effect modeling
  • Patient-level pooled analyses and meta-analyses
  • Consultation for investigators and trial teams

Flagship

VERITAS, ATLAS ER, the RESILIENT trials and HEMERA-1.

Request a consultation

AI and Digital Health

Models and decision support that bring the evidence to the bedside.

What we offer

  • Individualized treatment-effect models
  • Clinical decision support systems
  • Trial matching and workflow tools
  • Validation and deployment science

Flagship

The DUSK Tool, LUCID, TrialLens and ORASIS PRIME, with HORUS NeuroTechnologies as the commercial route.

2+ copyrighted software systems; PCT application (patent pending)

Imaging and Biological Biomarkers

Signals that explain who benefits, and why.

What we offer

  • Imaging assessment and validation
  • Biobanking
  • New and targeted biomarker discovery
  • Neuroprotection research

Flagship

Work on the recanalization paradox: why reopening the vessel does not always bring recovery.

Medical Device Development

From a bedside problem to a device in a partner's hands.

What we offer

  • Concept and engineering design
  • Bench testing and preclinical evaluation
  • Invention disclosure and IP strategy
  • Industry partnership

Flagship

Neurovascular device concepts from bench to invention disclosure.

2+ patents pending

Systems of Care and Quality

Faster, fairer access to treatment across a network.

What we offer

  • Triage and transfer optimization
  • Benchmarking and quality registries
  • Implementation and workflow evaluation

Flagship

AI-assisted scan sharing across four thrombectomy hubs and sixty spokes: 4,548 admissions (Journal of Neurology, Neurosurgery and Psychiatry, 2026).

Building the Next Generation

Capacity building and training through our scholar and research fellowship program.

What we offer

  • Scholar and research fellowship program
  • Mentorship
  • Methods education: trial design, statistics and critical appraisal
  • Global education

Flagship

Research fellows trained in trial design, statistics and translational methods.

Apply or ask about fellowships

Find your path

Sites

Join the DUSK trial and enroll patients with distal medium vessel occlusion stroke.

Join DUSK

Investigators

Statistical analysis plans, pooled analyses and methods support for your study.

Request a consultation